What to Expect: The Month-by-Month Timeline
Weight loss on GLP-1 medicines is front-loaded — most of it happens in the first 6 months — and gradually decelerates as the body finds a new set point. These curves come from published clinical trials, not from any individual patient.
Month 1
−2%
Appetite change begins, initial dose settling.
Month 3
−7%
Gating checkpoint — dose advance reviewed.
Month 6
−12%
Steady loss, dose likely at or near target.
Month 12
−15.2%
Approaching plateau, maintenance-focused.
This chart illustrates average population results from published clinical trials (STEP and SURMOUNT programmes), not a prediction of your individual outcome. Actual results depend on dose, adherence, diet, activity, and individual biology, and are supervised by your prescribing doctor. This is educational content, not medical advice.